IDH1 R132H mutation in a pilocytic astrocytoma: a case report.
نویسندگان
چکیده
We present the case of a 72-year old female with a right cerebellar pilocytic astrocytoma WHO grade I with an Isocitrate dehydrogenase 1 (IDH1) R132H mutation. The patient is recurrence-free 6 years after the initial diagnosis. Only one single case with strikingly similar clinicopathological features has been reported before. Otherwise, IDH1/2 mutations are not seen in pilocytic astrocytomas. The clinical implications of these findings are discussed.
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عنوان ژورنال:
- International journal of clinical and experimental pathology
دوره 8 9 شماره
صفحات -
تاریخ انتشار 2015